Anti-inflammatory compound inhibits production of molecules that cause destruction of cartilage and bone.
ANN ARBOR, MI – A new study from the University of Michigan Health System suggests that a compound in green tea may provide therapeutic benefits to people with rheumatoid arthritis.
The study looks at a potent anti-inflammatory compound derived from green tea. Researchers found that the compound – called epigallocatechin-3-gallate (EGCG) – inhibited the production of several molecules in the immune system that contribute to inflammation and joint damage in people with rheumatoid arthritis.
The compound from green tea also was found to suppress the inflammatory products in the connective tissue of people with rheumatoid arthritis.
To conduct the research, the scientists isolated cells called synovial fibroblasts from the joints of patients with rheumatoid arthritis. These fibroblasts – cells that form a lining of the tissue surrounding the capsule of the joints – then were cultured in a growth medium and incubated with the green tea compound. (SOURCE: Universidad de Michigan)
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